Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Coordination abnormal
ADR ID BADD_A01071
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.02      Coordination and balance disturbances
17.02.02.004      Coordination abnormal
Description Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions. [MeSH]
MedDRA Code 10010947
MeSH ID D001259
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Asynergia | Coordination abnormal | Coordination abnormal NOS | Coordination disturbance | Coordination impaired | Coordination was decreased | Decrease in coordination | Incoordination | Instability station | Lack of coordination | Muscular incoordination | One leg standing difficult | Sense of position abnormal | Station abnormal | Ataxia | Ataxias | Coordination Impairment | Coordination Impairments | Impairment, Coordination | Impairments, Coordination | Dyssynergia | Ataxy | Ataxia, Motor | Ataxias, Motor | Motor Ataxia | Motor Ataxias | Tremor, Rubral | Rubral Tremor | Rubral Tremors | Tremors, Rubral | Ataxia, Truncal | Ataxias, Truncal | Truncal Ataxia | Truncal Ataxias | Dyscoordination | Lack of Coordination | Coordination Lack | Incoordinations | Ataxia, Appendicular | Appendicular Ataxia | Appendicular Ataxias | Ataxias, Appendicular | Ataxia, Limb | Ataxias, Limb | Limb Ataxia | Limb Ataxias | Ataxia, Sensory | Ataxias, Sensory | Sensory Ataxia | Sensory Ataxias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01588Nortriptyline--
BADD_D01589Nortriptyline hydrochloride--
BADD_D01598Ofloxacin--
BADD_D01599Olanzapine--
BADD_D01617Ondansetron0.000150%
BADD_D01633Oxaliplatin0.000278%
BADD_D01637Oxcarbazepine0.001247%
BADD_D01654Palbociclib--
BADD_D01656Paliperidone--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01733Perampanel--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01764Phenylpropanolamine--
BADD_D01765Phenytoin0.005325%
BADD_D01766Phenytoin sodium--
BADD_D01767Phosphonatoformate--
BADD_D01798Pomalidomide--
BADD_D01817Pramipexole0.000730%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin0.001887%
BADD_D01854Promethazine--
BADD_D01855Promethazine hydrochloride--
BADD_D01872Protriptyline--
BADD_D01873Protriptyline hydrochloride--
BADD_D01888Quetiapine--
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